Collaboration, Translation And The Future Of Microbiome Innovation

April 17, 2019 root 0

Translation. When we hear this word, it may evoke feelings of excitement, adventure and possibility that come with learning different languages or travelling to a foreign country. For scientists, ‘translation’ also suggests moving research findings from the laboratory into clinical practice. Just as words are translated, so too are research findings.

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David Kyle, Evolve Biosystems

March 27, 2019 Jane 0

Dr. David Kyle has co-founded biotech companies for 35 years in nutrition and health including Martek Biosciences which was acquired in 2011 for $1.1 billion. For the first issue of Biostart, he spoke to us about the lessons he’s learned during his career.

Where did Evolve begin?

Evolve’s work is based on 15 years of previous research at the University of California at Davis. A cross-functional team of world-class scientists made an incredible discovery. The early microbiome of the infant is defined by the 15% of energy in human breast milk that is not directly available to the infant, but rather it is tied up in a soluble fibre (Human Milk Oligosaccharides or HMO) that feeds the new-born infant gut microbiome.

Interestingly, only a single bacterial species, Bifidobacterial infantis, has the capability for completely consuming all those HMO and remarkably, this species has been lost from most infants in the developed world due primarily to a lifetime exposure to antibiotics. The seeding of an infant’s gut microbiome has historically come from its mother’s gut microbiome, but mothers in the U.S. today have had 15-20 courses of antibiotics from the time they were born until the time they deliver their first baby. Her microbiome diversity has been depleted significantly, including this important symbiont and if mom does not have the B. infantis, she cannot pass it on to her baby and the symbiosis has…

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Editor’s Note: The Microbiome Special

March 6, 2019 Jane 0

Oxford is an inspiring place to live. Aside from the dreaming spires, famous alumni and culture of learning, it is home to an impressive number of biotech start-ups. Coupled with Cambridge and London, the number of start-ups in the area is booming.

I moved to Oxford, not for university like most do, but instead to work with scientists, helping them disseminate their knowledge, first through academic publishing and later in the conference industry. It’s been my pleasure to meet with scientists from all over the world, not just from the UK, but from across Europe, North America and Asia to find out not only what excites them about the future of the industry, but to discuss…

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3 Marketing Hacks for a Start-Up Business

February 27, 2019 root 0

For businesses just starting out, marketing can be a fickle beast. The focus for any start-up should be on doing a few things really well. So well that you outperform your competition. It almost doesn’t matter what marketing tactics you choose, as long as you abide by this principle. As it’s a new year, now is the perfect time to take stock and review. Here are 3 hacks that will help maximise your marketing in 2019.

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Defining The Microbiome Opportunity

February 20, 2019 root 0

One of the first challenges we encounter when considering the ‘Microbiome Opportunity’ is to describe exactly what we mean by it. Here, we visualize the opportunity as a multidimensional space that organizes itself along multiple axes.

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Charting A Translational Roadmap In The Microbiome Space

February 6, 2019 root 0

The opportunity afforded by the microbiome for developing therapeutic and wellness products is matched only by the formidable task of unraveling the science of the microbiome in the first place. Microbiome research is transitioning from a descriptive to a more mechanistic science, and progress in understanding mechanisms that underpin microbiome biology is likely to result in a surge of interest in this space on the part of the biotech, pharma and investor communities.

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